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Genomics Secondary Analysis Accelerated Solution - 
WASAI Lightning™ Family

Overview

WASAI-Lightning™ Family is an all-in-one DNA sequencing acceleration solution. With the integration of the Genome Analysis Toolkit (GATK), Intel Xeon CPU and its high-performance Programmable Acceleration Card, pipeline acceleration is sped up 11x the speed for a whole genome at 30x depth. WASAI Lighting Family shines by embracing the highly consistent standard pipeline, the simplified design for better ROI, and thus, improved user experience.

WASAI Lightning™–Accelerated Genomics Pipeline Performance

Whole Genome dataset NA12878 30X

●    BWA-MEM (0.7.17-r1188)
●    Sort & Markdup
●    GATK (4.0.x~4.1.x) HaplotypeCaller

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WASAI-Lightning™ consistently outperforms generic HPC competitors. The graph below shows three areas in which Lightning outperforms generic HPC competitors. 

WASAI Lightning™– Three Throughput Models Brings The Best ROI

WASAI-Lightning™ Family comes in three powerful forms to suit the needs of any client. With three different models at scaled power, this allows clients to purchase the model of Lightning that best suits the needs of their laboratory or research center. 

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Lightning: The basic model is more flexible to integrate with 1U/2U/Tower server. The daily throughput is 4.8 WGS per day per node. Suitable with small laboratories with the annual WGS sample needs no more than 1,800 WGS samples. 


Lightning S: The standard model supports 2U servers that come with a job scheduler which can support job-queueing for HPC clusters. The daily throughput is 8 WGS per day per node. The evolutionary solution can provide annual throughput of nearly 3000 WGS samples but with a more competitive price.


Lightning Plus: Lightning Plus is the high-end model brings the best daily throughput of 12 WGS on a single node. By the parallel execution on multiple FPGA cards, each genome data can get the fastest speed. This high-performance deployment has an extremely annual throughput of 4380. This model also comes with a job scheduler which can support job-queueing for HPC clusters.

WASAI Lightning™ Solution on Intel® FPGA Programmable Acceleration Card

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Qualified Server Information 

●    Intel PAC Arria® 10 GX
●    Intel PAC D5005 

WASAI Lightning Solution runs on the qualified FPGA servers with an aim to solve the bottlenecks of DNA data analysis.

Visualize your genomics analysis -
Simple and Easy to Use! 

The WASAI-Lightning™ Manager, a web-based system dashboard is simple and easy to use. It enables the genomics analysis to be automated, shortening the time for the whole analytic procedure. You can manage and monitor your genomics analysis status through our web application!

  • Plug-and-Play: real-time samples uploading and WASAI-Lightning™ pipeline execution

  • Time-saver Automation: genomics analysis automation to fasten the procedure

  • Easy to manage: analysis process monitoring and versions management

  • Ready to synchronize/share: analysis results sharing with the research team

  • Good Visualizationintuitive visual web-based demonstration of FASTQ data transformed into VCF

flexibility

Flexibility

Lightning can run most popular genome analysis tool. The convenience of using multiple workflow languages makes the genomics analysis more easily composable and flexible.

All-in-one pipeline

All-in-one pipeline

Lightning integrates FPGA card with server for easy deployment and the best performance.

reconfigurable

​Reconfigurable

We provide instant remote update for field programmable gate array (FPGA) to keep your system up-to-speed.

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Fast

Single Whole Genome Sequence sample is finished in 3 hours. 

cost-efficient

Cost-efficient

Offering best price that minimize the cost of the infrastructure and operation greatly improves efficiency.

accuracy & consistency

High Accuracy & Consistency

The acceleration is based on native algorithm BWA-MEA and GATK pipeline which are the most popular tools for secondary analysis.

Features

Application Field

Severe Acute Infectious Diseases Vaccines and Treatment Development (e.g. COVID-19)

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Prenatal and Postnatal Genetic Testing

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Population-based Cohort Study

Metagenomics

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Cancer & Rare Disease Research and Drug Development/ Repurposing

Preventive Genomics Testing Program

Precision Medicine Screening

Agrigenomics

On-premise Solution

●    Integrating Intel Programmable Acceleration Card and its qualified server
●    Accelerate GATK Best Practice Pipeline
●    WGS NA12878 at 30x coverage in 3 hours
●    The accuracy is consistent with GATK Best Practice
●    Applied to WGS and WES (Germline & Somatic)